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The TC/HDL Ratio is a calculation that compares Total Cholesterol (TC) to High-Density Lipoprotein (HDL) levels in the blood. It is used to assess cardiovascular risk. A lower ratio indicates a lower risk of heart disease, while a higher ratio suggests a higher risk of atherosclerosis, heart attack, or stroke. This ratio provides a more complete picture of heart health than total cholesterol alone and is usually part of a lipid profile.