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The Creatine Kinase (CK-NAC) test is a quantitative enzymatic assay performed on serum to measure the level of creatine kinase using the NAC (N-acetylcysteine) activated method. Creatine kinase is an enzyme found mainly in the heart, brain, and skeletal muscles, and elevated levels may indicate muscle damage, myocardial injury, muscular dystrophy, or other muscle-related disorders. This test is useful in the evaluation of muscle diseases and cardiac conditions. Results should be interpreted in correlation with clinical findings and other relevant investigations.