MBI036 - ALANINE AMINOTRANSFERASE (ALT/ SGPT), SERUM Detail

ALT plays an important role in amino acid metabolism. It catalyzes the transfer of an amino group from alanine to α-ketoglutarate, producing pyruvate and glutamate. This reaction is essential for energy production and normal liver function.

Clinical significance

• ALT is commonly measured in blood tests as a marker of liver health.

• Elevated ALT levels usually indicate liver cell injury or inflammation, such as:

  • Hepatitis (viral, alcoholic, or drug-induced)

  • Fatty liver disease

  • Liver cirrhosis

• Because ALT is more specific to the liver than many other enzymes, it is widely used to assess liver damage.

Normal range

• Typically 7–56 U/L (may vary depending on the laboratory).

In short, ALT is a key liver enzyme used clinically to evaluate liver function and damage.