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The Serum Free Thyroxine (FT4) test is a laboratory blood test used to measure the level of free (unbound) thyroxine hormone in the bloodstream. FT4 is one of the main hormones produced by the thyroid gland and plays a crucial role in regulating metabolism, energy levels, body temperature, heart function, and overall growth and development. The “free” portion represents the biologically active hormone that is available to body tissues, making this test more accurate for assessing true thyroid status compared to total T4. The FT4 test is commonly advised in the evaluation and monitoring of thyroid disorders such as hypothyroidism, hyperthyroidism, goiter, and pituitary gland dysfunction, as well as during thyroid hormone therapy. Abnormal FT4 levels may indicate an underactive or overactive thyroid gland, and results are typically interpreted along with TSH and FT3 levels for accurate clinical diagnosis.
"The following symptoms may indicate too little T3 and T4 in your body (hypothyroidism): trouble sleeping, tiredness and fatigue, difficulty concentrating, dry skin and hair, depression, sensitivity to cold temperature, frequent, heavy periods, joint and muscle pain."
"Normal values for TSH are 0.5 to 5.0 mIU/L. Pregnancy, a history of thyroid cancer, history of pituitary gland disease, and older age are some situations when TSH is optimally maintained in different ranges as guided by an endocrinologist. FT4 normal values are 0.7 to 1.9ng/dL."
"Generally, you don't need to fast before doing a thyroid function test. However, not fasting is sometimes linked to a lower TSH level. This means your results might not pick up on mild (subclinical) hypothyroidism - where your TSH levels are only mildly elevated."
"The commonest ones are Hashimoto's Disease. Some more are surgery on the thyroid gland, treatment with radiation, thyroid swelling, medicines, too little or too much Iodine, hypothyroidism at birth, damage to the pituitary gland."